Lab Research Project Manager, Nanoscale Biomedical Imaging Core Facility

Location
555 University Avenue, Toronto, ON M5G 1X8
 
Full job description
About SickKids

Dedicated exclusively to children and their families, The Hospital for Sick Children (SickKids) is one of the largest and most respected paediatric healthcare centres in the world. As innovators in child health, we lead and partner to improve the health of children through the integration of healthcare, leading-edge research and education. Our reputation would not have been built - nor could it be maintained - without the skills, knowledge and experience of the extraordinary people who come to work here every day. SickKids is committed to ongoing learning and development, and features a caring and supportive work environment that combines exceptionally high standards of practice.

When you join SickKids, you become part of our community. We share a commitment and determination to fulfill our vision of Healthier Children. A Better World.

Don't miss out on the opportunity to work alongside the world's best in paediatric healthcare.

Position Description

We have an opportunity for a Lab Research Project Manager in the High-resolution, High-throughput electron cryomicroscopy (cryo-EM) sub-core of the Nanoscale Biomedical Imaging Core Facility. The successful candidate will have experience with use of cryo-EM for high-resolution protein structure determination, will facilitate use of the sub-core.

Here's What You'll Get To Do:

Under guidance from experienced staff, maintain and continuously update a cryo-EM high-resolution, high-throughput structure determination pipeline
Train users to operate state-of-the-art cryo-EM microscopes and specimen preparation equipment, including an automated 200 kV cryo-EM specimen screening microscope and a 300 kV automated cryo-EM data collection microscope
Facilitate high-throughput data collection for cryo-EM research studies
Participate in collaborative projects to develop new cryo-EM approaches, working with research groups and instrument manufacturers
Work with research groups to determine high-resolution molecular structures for
biomedically important targets
Work with service engineers to ensure smooth operation of state-of-the-art cryo-EM
infrastructure
Be part of a team of facility staff, with opportunities to cross train on numerous
instruments
Participate in the smooth administration of a core facility
Perform image analysis for challenging structure determination problems and teach
trainees how to perform this analysis
Provide troubleshooting expertise as required to ensure integrity of imaging and image analysis systems
Maintain effective communication with students, postdoctoral fellows, scientific staff, principal investigators, and service engineers
Here's What You'll Need:

An MSc or PhD with experience with cryo-EM for protein structure determination
Minimum of 1 year of experience with cryo-EM.
Good technical skills in freezing specimens and computational image analysis
Experience with software packages such as cryoSPARC and/or Relion
Ability to work with minimal supervision in a team environment
Attention to detail
Excellent problem solving, communication, interpersonal, and organizational skills
Proficiency with computers
Demonstrated commitment to understanding and aiding in the pursuit of equity, diversity and inclusion objectives
Employment Type: Full time permanent 35 hours per week

Our Commitment to Diversity

SickKids is committed to championing equity, diversity and inclusion in all that we do, fostering an intentionally inclusive and culturally safe environment that reflects the diversity of the patients, families and communities we serve. Learn more about workplace inclusion.

Accessibility Accommodation

If you require accommodation during the application process, please reach out to our aSKHR team. SickKids can provide access and inclusion supports to eligible candidates to support their full engagement during the interview and selection process as well as to ensure candidates are able to perform their duties once successfully hired. If you are invited for an interview and require accommodation, please let us know at the time of your invitation to interview. Information received related to access, inclusion or accommodation will be addressed confidentially.

How To Apply

Technical difficulties? Email ask.hr@sickkids.ca with a short description of the issues you are experiencing. We will not accept resumes sent to this inbox but we are happy to respond to requests for technical assistance.

Tip: Combine your cover letter and resume into ONE document of 20 pages or less as you cannot upload multiple documents as part of your application.

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